Gitoxin

Overview

Gitoxin is a degradation metabolite of Digitoxin ( HY-B1357 ) and a non-competitive Na + /K + -ATPase inhibitor, with an IC 50 of 1.18e-6 M against the porcine high-affinity subtype and an IC 50 of 2.85e-5 M against the porcine low-affinity subtype. Gitoxin regulates atrial contractility and rhythmicity. Gitoxin is applicable to research related to congestive heart failure.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Heart Failure | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Na+/K+ ATPase

Product Information

• Catalog No.: HY-136933
• CAS No.: 4562-36-1
• Molecular Formula: C41H64O14
• Molecular Weight: 780.94
• Purity: 95.00%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source