SMA-12b

Overview

SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1β associated with inflammatory bodies and inhibites the production of IL-1β through a mechanism mediated by NRF2 . SMA-12b can be used in the study of rheumatoid arthritis (RA) and other autoimmune diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Others | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-137007
• CAS No.: 1496553-39-9
• Molecular Formula: C13H22INO2S
• Molecular Weight: 383.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source