SN-38 (Standard)

SN-38 (Standard)
  • CAS No.:86639-52-3
  • Grade:99.76%
  • Formula:C₂₂H₂₀N₂O₅
  • M.W.:392.40

Overview

SN-38 (Standard) is the analytical standard of SN-38. This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Topoisomerase

Product Information

  • Catalog No.: HY-13704R
  • CAS No.: 86639-52-3
  • Molecular Formula: C₂₂H₂₀N₂O₅
  • Molecular Weight: 392.40
  • Purity: 99.76%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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