SN-38-d 3

Overview

SN-38-d 3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC 50 s of 0.077 and 1.3 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-13704S
• CAS No.: 718612-49-8
• Molecular Formula: C22H17D3N2O5
• Molecular Weight: 395.42
• Purity: 98.79%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source