(+)-ITD-1

Overview

(+)-ITD-1 is an inhibitor for TGF-β , that inhibits the TGF-β2 with an IC 50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs).

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > TGF-β Receptor

Product Information

• Catalog No.: HY-137063
• CAS No.: 1409968-46-2
• Molecular Formula: C27H29NO3
• Molecular Weight: 415.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source