Taurolithocholic acid 3-sulfate disodium

Overview

Taurolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC 50 s of 71.6 and 69.4 (absence of Zn 2+ ) and 9 and 9.6 μM (presence of Zn 2+ ) in M39-20 and hGPR39-2 cells, respectively. Taurolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Taurolithocholic acid 3-sulfate disodium can be used for the research of gallbladder disease.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > GPR39

Product Information

• Catalog No.: HY-137255
• CAS No.: 64936-83-0
• Molecular Formula: C26H43NNa2O8S2
• Molecular Weight: 607.73
• Purity: 99.9%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.25 mg/mL (2.06 mM); Clear solution
• Availability: In-stock

Source

Original product source