DB-3-291

Overview

DB-3-291 is potent and selective CSK PROTAC degrader, with a K d of 1 nM. (Pink: Csk ligand ( HY-131669 ); Blue: Cereblon ligand ( HY-103597 ); Black: linker).

Application

Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Pain | Products > Disease Areas > Rheumatoid Arthritis | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > Src

Product Information

• Catalog No.: HY-137345
• CAS No.: 2769753-64-0
• Molecular Formula: C41H44ClN11O8S
• Molecular Weight: 886.37
• Purity: 99.08%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: 5 mg/mL (5.64 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source