OATD-01

Overview

OATD-01 is a highly potent, first-in-class, orally active and selective chitinase inhibitor with low nanomolar activity toward CHIT1 (hCHIT1, IC 50 =23 nM). OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets. OATD-01 exhibits significant antifibrotic efficacy in vivo and can be used for pulmonary fibrosis (IPF) research.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Glycosidase

Product Information

• Catalog No.: HY-137464A
• CAS No.: 2088453-21-6
• Molecular Formula: C19H27ClN6O
• Molecular Weight: 390.91
• Purity: 99.94%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (6.40 mM); Clear solution
• Availability: In-stock

Source

Original product source