ML267 free base

Overview

ML267 free base is a blood-brain barrier permeable Antibacterial agent and bacterial phosphopantetheinyl transferase ( PPTase ) inhibitor, with an IC 50 of 0.29 μM against Bacillus subtilis Sfp-PPTase and an IC 50 of 8.1 μM against bacterial AcpS-PPTase. ML267 free base attenuates bacterial secondary metabolism, activity, and the production of Sfp-PPTase -dependent metabolites. ML267 free base inhibits the growth of Gram-positive bacteria, including Methicillin ( HY-121544 )-resistant Staphylococcus aureus . ML267 free base is applicable to research related to bacterial infections, including methicillin-resistant Staphylococcus aureus infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Staphylococcus Aureus Infection | Products > Disease Areas > Bacillus Subtilis Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-137502A
• CAS No.: 1542213-03-5
• Molecular Formula: C17H17ClF3N5OS
• Molecular Weight: 431.86
• Purity: 98.45%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source