Tacrolimus

Overview

Tacrolimus (FK506), a molecular glue , a macrocyclic lactone, binds to FK506 binding protein ( FKBP ) to form a complex. Tacrolimus inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > FKBP | Products > Signaling Pathways > Molecular Glues | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Phosphatase

Product Information

• Catalog No.: HY-13756
• CAS No.: 104987-11-3
• Molecular Formula: C44H69NO12
• Molecular Weight: 804.02
• Purity: 99.93%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 2.75 mg/mL (3.42 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source