MANT-GppNHp

Overview

MANT-GppNHp is a competitive adenyl cyclase ( AC ) inhibitor. MANT-GppNHp is a fluorescently labeled GTP ( HY-113225 ) analogue. MANT-GppNHp interacts with the hydrophobic pocket near the AC catalytic site through its MANT group, thereby directly blocking the binding of the substrate ATP. MANT-GppNHp can be used to study diseases related to the increased activity of AC (such as cholera).

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Vibrio Cholerae Infection | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Adenylate Cyclase | Products > Signaling Pathways > Nucleoside Antimetabolite/Analog

Product Information

• Catalog No.: HY-137744
• CAS No.: 148821-01-6
• Molecular Formula: C18H24N7O14P3
• Molecular Weight: 655.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source