Ristocetin A sulfate

Overview

Ristocetin A sulfate (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor ( VWF ) and bacterial cell wall components. Ristocetin A sulfate interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation , Ristocetin A sulfate drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A sulfate not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A sulfate is widely used in studies related to thromboembolic diseases and bacterial infections.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Blood Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Platelet Disease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic

Product Information

• Catalog No.: HY-138053
• CAS No.: 90831-71-3
• Molecular Formula: C94H110N8O48S
• Molecular Weight: 2150.96
• Purity: 95.02%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source