7ß,27-Dihydroxycholesterol

Overview

7ß,27-Dihydroxycholesterol (7β, 27-OHC) is a potent and selective activator of RORγt (K i =120 nM). 7ß,27-Dihydroxycholesterol promotes the differentiation of mouse and human CD4 + Th17 cells. 7ß,27-Dihydroxycholesterol also increases the production of IL-17 depended on CYP27A1.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ROR

Product Information

• Catalog No.: HY-138115
• CAS No.: 240129-43-5
• Molecular Formula: C27H46O3
• Molecular Weight: 418.65
• Purity: 99.58%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source