Rosuvastatin lactone (Standard)

Overview

Rosuvastatin lactone (Standard) is the analytical standard of Rosuvastatin lactone. This product is intended for research and analytical applications. Rosuvastatin lactone is a metabolite of Rosuvastatin ( HY-17504A ), a statin lipid-lowering agent and HMG-CoA inhibitor. Rosuvastatin lactone exhibits endothelium-independent and HMG-CoA reductase-independent vasorelaxant activity in rat aortic rings, and its vasorelaxant effect is jointly mediated by NO produced by inducible nitric oxide synthase ( iNOS ) located in vascular smooth muscle and activation of potassium channels . Rosuvastatin lactone itself has no lipid-lowering effect.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Drug Metabolite | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-138166R
• CAS No.: 503610-43-3
• Molecular Formula: C22H26FN3O5S
• Molecular Weight: 463.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source