GW604714X

Overview

GW604714X is a potent inhibitor of mitochondrial respiration supported by pyruvate but not other substrates. GW604714X is a highly specific mitochondrial pyruvate carrier ( MPC ) inhibitor with a K i <0.1 nM. GW604714X also inhibits L-lactate transport by the plasma membrane monocarboxylate transporter ( MCT1 ), but at concentrations more than 4 orders of magnitude greater than the MPC.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

• Catalog No.: HY-138559
• CAS No.: 853953-65-8
• Molecular Formula: C21H18FN5O5S
• Molecular Weight: 471.46
• Purity: 98.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source