HPK1-IN-3

Overview

HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC 50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC 50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > MAP4K

Product Information

• Catalog No.: HY-138568
• CAS No.: 2739844-34-7
• Molecular Formula: C23H22F4N6O2
• Molecular Weight: 490.45
• Purity: 98.61%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.24 mM); Clear solution
• Availability: In-stock

Source

Original product source