Hydroxy-Dynasore

Overview

Hydroxy Dynasore (Dyngo-4a), a structural mimetic analog of Dynasore ( HY-15304 ), is an improved, less cytotoxic and versatile dynamin inhibitor with IC 50 values ​​of 0.38 μM and 2.3 μM for brain recombinant dynamin I and recombinant mouse dynamin II, respectively. Hydroxy Dynasore inhibits dynamin-dependent transferrin endocytosis with an IC 50 of 5.7 μM.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dynamin

Product Information

• Catalog No.: HY-13863
• CAS No.: 1256493-34-1
• Molecular Formula: C18H14N2O5
• Molecular Weight: 338.31
• Purity: 99.11%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (6.15 mM); Clear solution
• Availability: In-stock

Source

Original product source