ICCB-19 hydrochloride

Overview

ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride is indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and the degradation of long-lived proteins.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > RIP kinase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-138779
• CAS No.: 1803605-68-6
• Molecular Formula: C12H22ClN3OS
• Molecular Weight: 291.84
• Purity: 99.25%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.08 mg/mL (7.13 mM); Clear solution
• Availability: In-stock

Source

Original product source