XY028-140

Overview

XY028-140 is a PROTAC connected by ligands for Cereblon and CDK . XY028-140 inhibits both CDK4/6 expression and CDK4/6 activity in cancer cells. (Pink: Cdk6/cyclin D2 and CDK4 ligand ( HY-50767 ); Blue: Cereblon ligand ( HY-41547 ); Black: linker ( HY-W007408 )).

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-138946
• CAS No.: 2229974-83-6
• Molecular Formula: C39H40N10O7
• Molecular Weight: 760.80
• Purity: 98.52%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 0.56 mg/mL (0.74 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source