GK563

Overview

GK563 is a selective Ca 2+ -independent phospholipase A 2 ( GVIA iPLA 2 ) inhibitor with an IC 50 value of 1 nM. GK563 is 22000 times more active against GVIA iPLA 2 than GIVA cPLA 2 . GK563 reduces β-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phospholipase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-138990
• CAS No.: 2351820-19-2
• Molecular Formula: C16H22O2
• Molecular Weight: 246.34
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source