KVA-D-88

Overview

KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC 50 values of 140 and 880 nM for PDE4B and PDE4D , respectively. KVA-D-88 induces cAMP accumulation and inhibits neuroactive substance-mediated hyperlocomotion, locomotor sensitization. KVA-D-88 can be used for the research of drug addiction.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-139178
• CAS No.: 2410550-31-9
• Molecular Formula: C17H11Cl2F2N3O
• Molecular Weight: 382.19
• Purity: 99.81%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2 mg/mL (5.23 mM); Clear solution
• Availability: In-stock

Source

Original product source