PROTAC KRAS G12C degrader-1

Overview

PROTAC KRAS G12C degrader-1 is a Cereblon -based KRAS G12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRAS G12C dimerization and degrades GFP- KRAS G12C in reporter cells. (Pink: KRas G12C ligand ( HY-151014 ); Blue: Cereblon ligand ( HY-10984 ); Black: linker ( HY-W014883 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-139186
• CAS No.: 2984236-79-3
• Molecular Formula: C50H54ClFN8O6
• Molecular Weight: 917.47
• Purity: 99.15%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source