Brophenexin

Overview

Brophenexin (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. Brophenexin shows neuroprotective activity. Brophenexin prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC 50 of 2.1 μM. Brophenexin protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.

Application

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Product Information

• Catalog No.: HY-139192
• CAS No.: 2243506-33-2
• Molecular Formula: C11H19BrCl2N2
• Molecular Weight: 330.09
• Purity: 98.74%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.08 mg/mL (6.30 mM); Clear solution
• Availability: In-stock

Source

Original product source