PROTAC BRD4 Degrader-15

Overview

PROTAC BRD4 Degrader-15 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 , with IC 50 s of 7.2 nM and 8.1 nM for BRD4 BD1 and BD2 , respectively. PROTAC BRD4 Degrader-15 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. (Pink: BRD4 ligand ( HY-129939 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-184712 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-139294
• CAS No.: 2417370-67-1
• Molecular Formula: C57H62F2N10O10S2
• Molecular Weight: 1149.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source