TBI-223

Overview

TBI-223 is an orally active oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb). TBI-223 exhibits an IC 50 of 68 μg/mL for inhibiting mitochondrial protein synthesis (MPS) in HepG2 cells. TBI-223 is effective in three mouse models (bloodstream infection , skin infection , and bone infection ) of methicillin-resistant staphylococcus aureus infection . TBI-223 can be used for the study of tuberculosis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Mycobacterium Tuberculosis Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Antibiotic | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-139398
• CAS No.: 2071265-08-0
• Molecular Formula: C17H20FN3O5
• Molecular Weight: 365.36
• Purity: 99.73%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.84 mM); Clear solution
• Availability: In-stock

Source

Original product source