Parmodulin 2

Overview

Parmodulin 2 (ML161) is an allosteric inhibitor of protease-activated receptor 1 ( PAR1 ) with an IC 50 of 0.26 μM. Parmodulin 2 is a potent and non-competitive inhibitor of SFLLRN-induced P-selectin expression leading to inhibition of platelet aggregation in vitro and platelet thrombus formation in vivo.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Protease Activated Receptor (PAR)

Product Information

• Catalog No.: HY-13965
• CAS No.: 423735-93-7
• Molecular Formula: C17H17BrN2O2
• Molecular Weight: 361.23
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.92 mM); Clear solution
• Availability: In-stock

Source

Original product source