AMG 837 calcium hydrate

Overview

AMG 837 calcium hydrate is an orally active, selective GPR40 / FFA1 agonist with an EC 50 of 1.5 nM against human GPR40 . AMG 837 calcium hydrate stimulates insulin secretion in a glucose-dependent manner, and effectively improves glycemic control in both normal and diabetic rodent models . AMG 837 calcium hydrate binds to the BacA protein and impairs the survival and replication of Brucella . AMG 837 calcium hydrate can be used in research related to type 2 diabetes and brucellosis.

Application

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Product Information

• Catalog No.: HY-13967B
• CAS No.: 1259389-38-2
• Molecular Formula: C26H21F3O3.1/2Ca.H2O
• Molecular Weight: 455.45
• Purity: 99.00%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (5.49 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source