SPDP

Overview

SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > ADC Linkers

Product Information

• Catalog No.: HY-100216
• CAS No.: 68181-17-9
• Molecular Formula: C12H12N2O4S2
• Molecular Weight: 312.37
• Purity: 99.14%
• Storage: -20°C, protect from light, stored under nitrogen * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.08 mg/mL (6.66 mM); Clear solution
• Availability: In-stock

Source

Original product source