Pomalidomide-C5-Dovitinib is a heterobifunctional PROTAC that recruits KEAP1 E3 ligase to degrade BRD4 and BRD3 , but not BRD2 . (Pink: c-Kit and FLT3 ligand ( HY-50905 ); Blue: Cereblon ligand ( HY-130737 ); Black: linker ( HY-B0236 )).
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