FR183998 free base is a potent Na + /H + -exchange inhibitor, with IC 50 s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pH i change in rat lymphocytes, rat and human platelets, respectively.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Na+/H+ Exchanger (NHE)
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