R121919

Overview

R121919 (NBI30775) is a potent and selective CRF1R antagonist with a K i of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > CRFR

Product Information

• Catalog No.: HY-14127
• CAS No.: 195055-03-9
• Molecular Formula: C22H32N6
• Molecular Weight: 380.53
• Purity: 99.66%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.57 mM); Clear solution
• Availability: In-stock

Source

Original product source