YM-53601

Overview

YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC 50 of 79 nM. Lipid-lowering agent. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 ( FDFT1 ) enzyme activity and abrogates HCV propagation.

Application

Products | Products > Disease Areas > Hepatitis Virus Infection | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Viral Infection | Products > Disease Areas > Hepatitis C Virus Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Metabolic Disease | Products > Research Areas > Infection | Products > Signaling Pathways > Farnesyl Transferase | Products > Signaling Pathways > HCV

Product Information

• Catalog No.: HY-100313A
• CAS No.: 182959-33-7
• Molecular Formula: C21H22ClFN2O
• Molecular Weight: 372.86
• Purity: 98.23%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (6.70 mM); Clear solution
• Availability: In-stock

Source

Original product source