Tegaserod-d 11

Overview

Tegaserod -d 11 is deuterated labeled Tegaserod ( HY-14153 ). Tegaserod is an orally active serotonin receptor 4 ( HTR4 ; 5-HT 4 R ) agonist and a 5-HT 2B receptor antagonist. Tegaserod has pK i s of 7.5, 8.4 and 7.0 for human recombinant 5-HT 2A , 5-HT 2B and 5-HT 2C receptors, respectively. Tegaserod causes tumor cell apoptosis , blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Others | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Isotope-Labeled Compounds

Product Information

• Catalog No.: HY-14153S
• CAS No.: 1134188-56-9
• Molecular Formula: C16H12D11N5O
• Molecular Weight: 312.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source