ZA10

Overview

ZA10 is a selective TRPM2 channel inhibitor, with an IC 50 value of 8.1 μM. ZA10 can effectively suppress intracellular Ca 2+ overload triggered by TRPM2 channel activation. ZA10 significantly reduce the mortality of SH-SY5Y cells induced by H2O2. ZA10 can be used for the study of ischemia-reperfusion injury, inflammation, or other neurodegenerative diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-141713
• CAS No.: 2696407-24-4
• Molecular Formula: C25H26N4O2
• Molecular Weight: 414.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source