MS21

Overview

MS21 is an effective AKT PROTAC degrader. MS21 can inhibit mutations in the PI3K/PTEN pathway, suppress the proliferation and induce cell cycle arrest of tumor cells. MS21 has anti-tumor activity. (Pink: AKT ligand-2 ( HY-48682 ); Black: Linker ( HY-W014125 ); Blue: (S,R,S)-AHPC ( HY-125845 )). (Pink: Akt ligand ( HY-48682 ); Blue: VHL ligand ( HY-125845 ); Black: linker ( HY-W014125 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Akt

Product Information

• Catalog No.: HY-141807
• CAS No.: 2376137-05-0
• Molecular Formula: C58H79ClN12O6S
• Molecular Weight: 1107.84
• Purity: 99.64%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source