STAMBP-IN-1

Overview

STAMBP-IN-1 is a small-molecule inhibitor of STAMBP deubiquitinase , and interrupts STAMBP-Ub-NALP7 interaction. STAMBP-IN-1 decreases protein level of its inflammasome substrate NALP7 and suppresses IL-1b release after Toll-like receptor (TLR) agonism. STAMBP-IN-1 inhibits the activity of STAMBP to cleave recombinant di-Ub with an IC 50 value of 0.33 mM.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Deubiquitinase

Product Information

• Catalog No.: HY-141852
• CAS No.: 896683-78-6
• Molecular Formula: C27H28N4O4S
• Molecular Weight: 504.60
• Purity: 98.73%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source