Amiodarone

Overview

Amiodarone, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outward ionic current (IhERG) tails with an IC 50 of ∼45 nM. Amiodarone induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts. Amiodarone can be used in the research of both supraventricular and ventricular arrhythmias.

Application

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Product Information

• Catalog No.: HY-14187
• CAS No.: 1951-25-3
• Molecular Formula: C25H29I2NO3
• Molecular Weight: 645.31
• Purity: 98.32%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (3.87 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source