Toloxatone

Overview

Toloxatone (MD 69276) is a reversible, selective MAO-A inhibitor that can cross the blood-brain barrier. Toloxatone increases the levels of serotonin (5-HT) and norepinephrine in the brain. Toloxatone reduces the immobility time in the forced swimming test in mice, inhibits killing behavior in rats without causing sedation, and shows a correlation between its free plasma concentration and cerebrospinal fluid concentration. Toloxatone is widely used in research related to depression, depressive disorders and Parkinson's disease.

Application

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Product Information

• Catalog No.: HY-14196
• CAS No.: 29218-27-7
• Molecular Formula: C11H13NO3
• Molecular Weight: 207.23
• Purity: 98.11%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (10.04 mM); Clear solution
• Availability: In-stock

Source

Original product source