Dapivirine hydrochloride

Dapivirine hydrochloride
  • CAS No.:244768-47-6
  • Grade:99.98%
  • Formula:C20H20ClN5
  • M.W.:365.86

Overview

Dapivirine hydrochloride is a non-nucleoside reverse transcriptase inhibitor with antitumor activity. Dapivirine hydrochloride attenuates the proliferation of glioblastoma cells and induces apoptosis . Dapivirine hydrochloride modulates autophagy and activates Akt , Bad, and SAPK/JNK signaling pathways. Dapivirine hydrochloride has shown inhibitory effects on glioma cell growth both in vitro and in vivo. Dapivirine hydrochloride is also a promising drug candidate for topical microbial agents for the prevention of sexual transmission of HIV-1 .

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Reverse Transcriptase

Product Information

  • Catalog No.: HY-14266A
  • CAS No.: 244768-47-6
  • Molecular Formula: C20H20ClN5
  • Molecular Weight: 365.86
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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