SGK1-IN-3 (Compound 3a) is an ATP-competitive SGK1 inhibitor with an IC 50 of <1 nM against hSGK1. SGK1-IN-3 blocks the activity of CDK family members. SGK1-IN-3 is a P-glycoprotein substrate. SGK1-IN-3 can be used for research on osteoarthritis.
Products | Products > Disease Areas > Arthritis | Products > Disease Areas > Osteoarthritis | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > SGK | Products > Signaling Pathways > P-glycoprotein | Products > Signaling Pathways > CDK
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