Vildagliptin - 13 C 5 , 15 N (LAF237- 13 C 5 , 15 N; NVP-LAF 237- 13 C 5 , 15 N) is a 13 C- and 15 N-labeled Vildagliptin ( HY-14291 ). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV ( DPP-IV ) inhibitor with an IC 50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.
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