Vilanterol (GW642444) trifenatate is a long-acting β 2 adrenergic receptor agonist. Vilanterol trifenatate has pEC 50 values for β 2 -AR, β 1 -AR, and β 3 -AR of 9.4, 6.4, and 6.1, respectively. Vilanterol trifenatate selectively activates airway β 2 adrenergic receptors, increases cAMP and thus relaxes bronchial smooth muscle. Vilanterol trifenatate can be used in asthma research [2][4] .
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