Diroximel fumarate

Overview

Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity.

Application

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Product Information

• Catalog No.: HY-100375
• CAS No.: 1577222-14-0
• Molecular Formula: C11H13NO6
• Molecular Weight: 255.22
• Purity: 99.60%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.08 mg/mL (8.15 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source