ABT-724

Overview

ABT-724, a chemical probe, is a potent and highly selective dopamine D 4 receptor agonist with an EC 50 of 12.4 nM for human dopamine D 4 receptor . ABT-724 is a potent partial agonist at the rat D 4 ( EC 50 of 14.3 nM) and the ferret D 4 receptor ( EC 50 of 23.2 nM). ABT-724 has no effect on dopamine D 1 , D 2 , D 3 , or D 5 receptors. ABT-724 could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Receptor

Product Information

• Catalog No.: HY-14330
• CAS No.: 70006-24-5
• Molecular Formula: C17H19N5
• Molecular Weight: 293.37
• Purity: 98.04%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source