V-0219 hydrochloride

Overview

V-0219 hydrochloride is an orally active glucagon-like peptide-1 receptor ( GLP-1R ) positive allosteric modulator. V-0219 hydrochloride potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 hydrochloride potentiates glucose-dependent insulin secretion. V-0219 hydrochloride improves glucose handling in normal and diabetic rodents. V-0219 hydrochloride can be used for the research of obesity-associated diabetes.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-143312A
• CAS No.: 2922283-73-4
• Molecular Formula: C20H26ClF3N4O2
• Molecular Weight: 446.89
• Purity: 99.39%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution
• Availability: In-stock

Source

Original product source