Nigericin sodium salt (Standard)

Overview

Nigericin (sodium salt) (Standard) is the analytical standard of Nigericin (sodium salt). This product is intended for research and analytical applications. Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K + /H + ionophore , promoting K + /H + exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt / β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1 /GSDMD in TNBC.

Application

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Product Information

• Catalog No.: HY-100381R
• CAS No.: 28643-80-3
• Molecular Formula: C40H67NaO11
• Molecular Weight: 746.94
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source