MK-5046

Overview

MK-5046 is a potent, selective and orally active Bombesin receptor subtype-3 ( BRS-3 ) allosteric agonist with an IC 50 and an EC 50 value of 27 and 25 nM for hBRS-3, respectively. MK-5046 inhibits food intake and reduces body weight of diet-induced obese (DIO) mouse models. MK-5046 can be used for the research of obesity.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Bombesin Receptor

Product Information

• Catalog No.: HY-14342
• CAS No.: 1022152-70-0
• Molecular Formula: C20H18F6N4O
• Molecular Weight: 444.37
• Purity: 99.75%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1.43 mg/mL (3.22 mM); Clear solution
• Availability: In-stock

Source

Original product source