Allolithocholic acid (Standard)

Overview

Allolithocholic acid (Standard) is the analytical standard of Allolithocholic acid ( HY-143712 ). This product is intended for research and analytical applications. Allolithocholic acid is an orally active metabolite of Lithocholic acid ( HY-B0172 ). Allolithocholic acid is a dual GPBAR1 agonist ( EC 50 = 2.7 μM) and RORγt inverse agonist ( IC 50 = 3.4 μM). Allolithocholic acid modulates immune and metabolic pathways, regulates immune cell polarization, prevents M1 macrophage and Th17 CD4 cell polarization. Allolithocholic acid improves insulin sensitivity, reduces liver lipid accumulation, reverses liver immunological, inflammatory and metabolic signaling dysregulation, restores bile acid homeostasis, adipose tissue histopathology/function, and intestinal microbiota composition, modulates intestinal immunity. Allolithocholic acid can be used for the researches of cancer , inflammayion, immunology and metabolic disease .

Application

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Product Information

• Catalog No.: HY-143712R
• CAS No.: 2276-94-0
• Molecular Formula: C24H40O3
• Molecular Weight: 376.57
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source