VU0361737

Overview

VU0361737 (ML-128) is a potent, selective and CNS penetrant positive allosteric modulator of metabotropic glutamate receptor 4 ( mGluR 4 PAM ), with EC 50 s of 240 nM and 110 nM for human and rat mGluR 4 receptors, respectively. VU0361737 has neuroprotective effect. VU0361737 is potential for Parkinson's disease research .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR

Product Information

• Catalog No.: HY-14418
• CAS No.: 1161205-04-4
• Molecular Formula: C13H11ClN2O2
• Molecular Weight: 262.69
• Purity: 99.65%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (9.52 mM); Clear solution
• Availability: In-stock

Source

Original product source