Soraprazan

Overview

Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase ( K i =6.4 nM), with an IC 50 of 0.19 μM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Proton Pump

Product Information

• Catalog No.: HY-100414
• CAS No.: 261944-46-1
• Molecular Formula: C21H25N3O3
• Molecular Weight: 367.44
• Purity: 99.78%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 5 mg/mL (13.61 mM); Clear solution
• Availability: In-stock

Source

Original product source